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--> SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE DEPARTMENT OF PATHOLOGY 札幌医科大学医学部 病理学第一講座 ストレスバイオロジー 癌幹細胞 骨軟部腫瘍 がん抗原の網羅的探索 上皮とアレルギー 臨床研究に関する情報 --> 2000.00.00 ■■■ --> 2024.05.01 J Dermatol. Shogase N et al. “Characterization of CD4 T-cell phenotype in human leukocyte antigen class II-positive acral melanoma.” 2024.05.01 Anticancer Res. Satoyoshi T et al. “CD8-positive T Cell Infiltration With Human Leukocyte Antigen Class 1 Expression Predicts Patients With Stage IV Colorectal Cancer Survival.” 2024.05.01 Biochem Biophys Res Commun. Kubo T et al. “Distinct induction pathways of heat shock protein 27 in human keratinocytes: Heat stimulation or capsaicin through phosphorylation of heat shock factor 1 at serine 326 and/or suppression of ΔNp63.” 2024.05.01 J Cancer Res Clin Oncol. 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Wang L et al.”LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells.” 2017.6.21 Biochem Biophys Res Commun. Takeda R et al.”Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells.” 2017.6.21 Oncotarget. Tanaka T et al.”Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer.” 2017.1.19 Nihon Rinsho Meneki Gakkai Kaishi.Kubo T et al.” Dendritic cell and cancer immune checkpoint.” 2017.1.19 Eur J Immunol. Kajiwara T et al.”Hypoxia augments MHC class I antigen presentation via facilitation of ERO1-α-mediated oxidative folding in murine tumor cells.” 2017.1.19 イベントに冬期研修会プログラム(2016 Winter)を追加しました。 佐藤昇志名誉教授が第２１回日本癌学会「長與又郎賞」を授賞いたしました。 2016.8.30 Oncoimmunology. Murata K et al.”Identification of a novel human memory T-cell population with the characteristics of stem-like chemo-resistance.” 2016.8.30 Pathol Int. Tsukahara T et al.”Peptide vaccination therapy: Towards the next generation.” 2016.8.30 Oncotarget. Saijo H et al.”Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress.” 2016.8.30 PLoS One. Takaya A et al.”Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480.” 2016.8.30 PLoS One. Sato A et al.”Novel Mechanisms of Compromised Lymphatic Endothelial Cell Homeostasis in Obesity: The Role of Leptin in Lymphatic Endothelial Cell Tube Formation and Proliferation.” 2016.8.30 Anticancer Res. Shima H et al.”SOX2 and ALDH1 as Predictors of Operable Breast Cancer.” 2016.8.30 Nihon Rinsho Meneki Gakkai Kaishi.Murata K et al.”Cancer immunotherapy and immunological memory.” 菊地浩吉名誉教授が平成２７年度北海道大学大学院医学研究科・医学部医学科「特別賞」を授賞いたしました。 2016.7.1 イベントに夏期研修会プログラム(2016 Summer)を追加しました。 2016.5.19 Expert Opin Biol Ther. 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Hirohashi Y et al.”HLA class I as a predictor of clinical prognosis and CTL infiltration as a predictor of chemosensitivity in ovarian cancer.” 2015.7.17 Surg Today. Okita K et al.”Pancreatic regeneration: basic research and gene regulation.” 2015.7.17 Immunol Lett. Tanaka T et al.”CpG-A stimulates Hsp72 secretion from plasmacytoid dendritic cells, facilitating cross-presentation.” 2015.7.17 J Surg Oncol. Emori M et al.”Prognostic impact of CD109 expression in myxofibrosarcoma.” 2015.7.16 イベントに夏期研修会プログラム(2015 Summer)を追加しました。 2015.5.19 World J Surg Oncol. Iwayama Y et al.” Prognostic value of HLA class I expression in patients with colorectal cancer.” 2015.5.19 Eur J Immunol. Saito K et al.”Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE.” 2015.5.19 J Immunol. Kukita K et al.”Cancer-Associated Oxidase ERO1-α Regulates the Expression of MHC Class I Molecule via Oxidative Folding.” 2015.5.19 Surg Today. Mizuguchi T et al.”Trials of vaccines for pancreatic ductal adenocarcinoma: Is there any hope of an improved prognosis?” 2015.5.19 病理夏の学校のお知らせ 2015年7月4日(土)～5日(日) 詳しくはこちらをご参照下さい。 2015.2.2 J Immunol. Tanaka T et al. ”Cancer-Associated Oxidoreductase ERO1-α Drives the Production of Tumor-Promoting Myeloid-Derived Suppressor Cells via Oxidative Protein Folding.” 2015.2.2 Anticancer Res. Nishida S et al. “ Expression of hepatocyte growth factor in prostate cancer may indicate a biochemical recurrence after radical prostatectomy.” 2015.2.2 Lung Cancer. Kitai H et al. “ Spontaneous regression of small cell lung cancer combined with cancer associated retinopathy.” 2015.2.2 Biochem Biophys Res Commun. Kubo T et al. “Tight junction protein claudin-4 is modulated via ΔNp63 in human keratinocytes.” 2015.2.2 Cancer Sci. Tanaka T et al. “Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells.” 2015.1.6 進行膵臓がんのペプチドワクチン治験参加者の募集をリンクしました。詳しくはこちらをご参照下さい。 2014.12.8 イベントに冬期研修会プログラム(2014 Winter)を追加しました。 2014.11.11 Immunobiology. Kasamatsu J et al. “PolyI:C and mouse survivin artificially embedding human 2B peptide induce a CD4+ T cell response to autologous survivin in HLA-A*2402 transgenic mice.” 2014.11.11 Cancer Immunol Res. Mariya T et al. “Prognostic impact of human leukocyte antigen class I expression and association of platinum resistance with immunological profiles in epithelial ovarian cancer.” 2014.11.11 Lab Invest. Yasuda K et al. “Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity.” 2014.9.22 PLoS One. 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Shastri N et al. “Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum.” 2014.6.18 イベントに夏期研修会プログラム(2014 Summer)を追加しました。 2014.2.3 J Cancer Res Clin Oncol. Tanaka T et al. "Hypoxia-inducible factor (HIF)-independent expression mechanism and novel function of HIF prolyl hydroxylase-3 in renal cell carcinoma." 2014.2.3 Cancer Sci. Morita R et al. "Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells." 2014.2.3 PLoS One. Emori M et al. "High Expression of CD109 Antigen Regulates the Phenotype of Cancer Stem-Like Cells/Cancer-Initiating Cells in the Novel Epithelioid Sarcoma Cell Line ESX and Is Related to Poor Prognosis of Soft Tissue Sarcoma." 2014.2.3 Clin Dev Immnunol. Tanaka T et al. 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"ALDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and ALDH1 high expression is associated with poor prognosis." 2013.7.12 イベントに夏期研修会プログラム(2013 Summer)を追加しました。 2013.5.15 第10回 病理 夏の学校（札幌）のお知らせです。こちらの案内ポスターとスケジュールをご覧ください。 2013.4.26 Tissue Antigens. Yamada R et al. "Preferential expression of cancer/testis genes in cancer stem-like cells: proposal of a novel sub-category, cancer/testis/stem gene." 2013.4.26 Cancer Science. Kutomi G et al. "Human Endoplasmic Reticulum Oxidoreductin 1-α (hERO1-α) is a Novel Predictor for Poor Prognosis of Breast Cancer." 2013.4.26 Nihon Rinsyo. Tamura Y et al. "Heat shock protein inhibitor for molecular targeting therapy." 2013.4.24 Peopleを更新しました。 第102回日本病理学会総会へのリンクはこちらです。 2013.1.23 Methods in Molecular Biology. Kanaseki T et al. "Biochemical analysis of naturally processed antigenic peptides presented by MHC class I molecules." 2013.1.23 Cancer Science. Nishida S et al. "Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor." 2013.1.23 Gan to Kagaku Ryoho. Kukita K et al. "Human endoplasmic reticulum oxidoreductin 1-like α regulates immune response of cancer cells via modulation of major histocompatibility complex class I expression and oxidation." 2013.1.23 Anticancer Research. Kiriyama K et al. "Expression and Function of FERMT Genes in Colon Carcinoma Cells." 2013.1.23 Virchows Arch. Kitamura H et al. "Nuclear, but not cytoplasmic, localization of survivin as a negative prognostic factor for survival in upper urinary tract urothelial carcinoma." 2012.12.12 イベントに冬期研修会プログラム(2012 Winter)を追加しました。 2012.11.8 Cancer Science. Kameshima H et al. "Immunotherapeutic benefit of IFNα in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients." 2012.11.8 Exp Mol Pathol. Morita R et al. "DNA methyltransferase 1 is essential for initiation of the colon cancers." 2012.11.8 Pathol Int. 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"HSP DNAJB8 Controls Tumor-Initiating Ability in Renal Cancer Stem-like Cells." 2012.5.28 Pathology International. Torigoe T et al. "Establishment of a monoclonal anti-pan HLA class I antibody suitable for immunostaining of formalin-fixed tissue:..." 2012.5.28 第71回日本癌学会学術総会へのリンクはこちらです。 2012.5.28 ホームページをリニューアルしました。 〒060-8556 札幌市中央区南1条西17丁目　札幌医科大学医学部 病理学第一講座　TEL 011-611-2111 （内線26910） FAX 011-643-2310 © 2012 Department of Pathology, Sapporo Medical University, Sapporo, Japan